Publications

Drilon A, Camidge DR, Lin JJ, Kim SW, Solomon BJ, Dziadziuszko R, Besse B, Goto K, de Langen AJ, Wolf J, Lee KH, Popat S, Springfeld C, Nagasaka M, Felip E, Yang N, Velcheti V, Lu S, Kao S, Dooms C, Krebs MG, Yao W, Beg MS, Hu X, Moro-Sibilot D, Cheema P, Stopatschinskaja S, Mehta M, Trone D, Graber A, Sims G, Yuan Y, Cho BC, Trident-1 Investigators. Repotrectinib in ROS1 Fusion-Positive Non-Small-Cell Lung Cancer. N Engl J Med. 2024 Jan 11;390(2):118-31. doi: 10.1056/NEJMoa2302299. PMID: 38197815.

Nindra U, Bray V, Karikios D, Shafiei M, Subramaniam S, Ding P, Kao S, Pal A. Variations in patterns of prescribing durvalumab in stage III lung cancer: a survey of Australian Medical Oncologists. Oncology. 2024;102(8):732-6. doi: 10.1159/000535855. Epub 2024 Jan 17. PMID: 38232722.

Brown LJ, Khou V, Brown C, Alexander M, Jayamanne D, Wei J, Gray L, Chan WY, Smith S, Harden S, Mersiades A, Warburton L, Itchins M, Lee JH, Pavlakis N, Clarke SJ, Boyer M, Nagrial A, Hau E, Pires da Silva I, Kao S, Kong BY. First-line chemoimmunotherapy and immunotherapy in patients with non-small cell lung cancer and brain metastases: a registry study. Front Oncol. 2024 Feb 7;14:1305720. doi: 10.3389/fonc.2024.1305720. eCollection 2024. PMID: 38406805.

Alexander M, Rogers J, Parakh S, Mitchell P, Clay TD, Kao S, Hughes BGM, Itchins M, Kong BY, Pavlakis N, Solomon BJ, John T. Lurbinectedin in small cell lung cancer: real-world experience of a multicentre national early access programme. Intern Med J. 2024 Jul;54(7):1087-96. doi: 10.1111/imj.16348. Epub 2024 Feb 18. PMID: 38369719.

O Parsonson A, Grimison P, Boyer M, Horvath L, Mahon K, Beith J, Kao S, Hui M, Sutherland S, Kumar S, Heller G, McNeil C. Patient satisfaction with telehealth consultations in medical oncology clinics: A cross-sectional study at a metropolitan centre during the COVID-19 pandemic. J Telemed Telecare. 2024 Feb;30(2):320-6. doi: 10.1177/1357633X211045586. Epub 2021 Oct 16. PMID: 34657513.

Nindra U, Shahnam A, Stevens S, Pal A, Nagrial A, Lee J, Yip PY, Adam T, Boyer M, Kao S, Bray V. Influence of EGFR mutation status and PD-L1 expression in stage III unresectable non-small cell lung cancer treated with chemoradiation and consolidation durvalumab. Asia Pac J Clin Oncol. 2024 Feb;20(1):16-24. doi: 10.1111/ajco.13940. Epub 2023 Feb 28. PMID: 36855021.

Tan L, Brown C, Mersiades A, Lee CK, John T, Kao S, Newnham G, O’Byrne K, Parakh S, Bray V, Jasas K, Yip S, Wong SQ, Ftouni S, Guinto J, Chandrashekar S, Clarke S, Pavlakis N, Stockler MR, Dawson SJ, Solomon BJ. A Phase II trial of alternating osimertinib and gefitinib therapy in advanced EGFR-T790M positive non-small cell lung cancer: OSCILLATE. Nat Commun. 2024 Feb 28;15(1):1823. doi: 10.1038/s41467-024-46008-1. PMID: 38418463.

Dwyer LJ, Singhal N, Yu B, Kao S. Successful Osimertinib Rechallenge After Relapse Following Adjuvant Osimertinib: A Case Report. J Thorac Oncol. 2024 Apr;19(4):650-2. doi: 10.1016/j.jtho.2024.01.001. Epub 2024 Feb 9. PMID: 38340108.

Heynemann S, Vanguru V, Adelstein S, Kao S. Hemophagocytic lymphohistiocytosis (HLH) and cytokine release syndrome (CRS) in a patient with oncogene-addicted metastatic non-small cell lung cancer (NSCLC) following combination chemotherapy-immunotherapy. Asia Pac J Clin Oncol. 2024 Apr;20(2):315-8. doi: 10.1111/ajco.13906. Epub 2022 Dec 23. PMID: 36562695.

McNamee N, Harvey C, Gray L, Khoo T, Lingam L, Zhang B, Nindra U, Yip PY, Pal A, Clay T, Arulananda S, Itchins M, Pavlakis N, Kao S, Bowyer S, Chin V, Warburton L, Pires da Silva I, John T, Solomon B, Alexander M, Nagrial A. Brief Report: Real-World Toxicity and Survival of Combination Immunotherapy in Pleural Mesothelioma-RIOMeso. J Thorac Oncol. 2024 Apr;19(4):636-42. doi: 10.1016/j.jtho.2023.11.014. Epub 2023 Nov 28. PMID: 38036250.

Wu YL, Dziadziuszko R, Ahn JS, Barlesi F, Nishio M, Lee DH, Lee JS, Zhong W, Horinouchi H, Mao W, Hochmair M, de Marinis F, Migliorino MR, Bondarenko I, Lu S, Wang Q, Ochi Lohmann T, Xu T, Cardona A, Ruf T, Noe J, Solomon BJ, ALINA Investigators (Kao S, included). Alectinib in Resected ALK-Positive Non-Small-Cell Lung Cancer. N Engl J Med. 2024 Apr 11;390(14):1265-76. doi: 10.1056/NEJMoa2310532. PMID: 38598794.

Smith S, Kao S, Boyer M, Franco M, Moore M. Treatment selection and real-world analysis of immunotherapy with or without chemotherapy in PD-L1-high metastatic non-small cell lung cancer. Intern Med J. 2024 Aug;54(8):1337-43. doi: 10.1111/imj.16389. Epub 2024 Apr 15. PMID: 38622825.

Balaji P, Barry MA, Tran VT, Marschner S, Lu J, Nguyen DM, Mina A, Bandodkar S, Alvarez S, James V, Ronquillo J, Varikatt W, Kovoor P, McEwan A, Thiagalingam A, Thomas SP, Qian PC. Long-Term Safety and Efficacy of Transcatheter Microwave and Radiofrequency Denervation in a Chronic Ovine Model. J Am Heart Assoc. 2024 May 7;13(9):e031795. doi: 10.1161/JAHA.123.031795. Epub 2024 Apr 25. PMID: 38664237.

Xue YX, Lei BY, Feng X, Ye MG, Hazelton P, Huang Y, Fan XF, Zhu GY, Robertson N, Hosseini-Beheshti E, Chen XF. A novel dye-sensitised solar cell based portable sensor for chemical detection. Sensors and Actuators B-Chemical. 2024 Mar 15;403:135123.  doi: 10.1016/j.snb.2023.135123.

Farahani MS, Hosseini-Beheshti E, Moazzeni SM, Moghadam MF. Engineered extracellular vesicles expressing ICAM-1: A promising targeted delivery system for T cell modifications. Biochim Biophys Acta Gen Subj. 2024 Mar;1868(3):130541.  doi: 10.1016/j.bbagen.2023.130541. Epub 2023 Dec 15.  PMID: 38103755.

Welsh JA, Goberdhan DCI, O’Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrugger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Moller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku’ulei-Lyn Faustino V, Kyburz D, Lasser C, Lennon KM, Lotvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ, MISEV Consortium (Hosseini‐Beheshti E, included), Thery C, Witwer KW. Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. J Extracell Vesicles. 2024 Feb;13(2):e12404.  doi: 10.1002/jev2.12404.  PMID: 38326288.

Stevens S, Nindra U, Shahnam A, Wei J, Bray V, Pal A, Yip PY, Linton A, Blinman P, Nagrial A, Lee J, Boyer M, Kao S. Real world efficacy and toxicity of consolidation durvalumab following chemoradiotherapy in older Australian patients with unresectable stage III non-small cell lung cancer. J Geriatr Oncol. 2024 Mar;15(2):101705.  doi: 10.1016/j.jgo.2024.101705. Epub 2024 Jan 29.  PMID: 38290173.

Alexander M, Wei J, Parakh S, John T, Kao S, Nagrial A, Bowyer S, Warburton L, Moore M, Hughes BGM, Clay TD, Pavlakis N, Solomon BJ, Itchins M. LOREALAUS: LOrlatinib REAL-World AUStralian Experience in Advanced ALK-Rearranged NSCLC. JTO Clin Res Rep. 2023 Feb 26;4(4):100490. doi: 10.1016/j.jtocrr.2023.100490. eCollection 2023 Apr. PMID: 37077199.

Yeo D, Kao S, Gupta R, Wahlroos S, Bastian A, Strauss H, Klemm V, Shrestha P, Ramirez AB, Costandy L, Huston R, Gardner BS, Grimison P, Clark JR, Rasko JEJ. Accurate isolation and detection of circulating tumor cells using enrichment-free multiparametric high resolution imaging. Front Oncol. 2023 Mar 27;13:1141228. doi: 10.3389/fonc.2023.1141228. eCollection 2023. PMID: 37051527.

Shi H, Zhang L, Yu TK, Zhuang L, Ke H, Johnson B, Rath E, Lee K, Klebe S, Kao S, Qin KL, Pham HNT, Vuong Q, Cheng YY. Leptospermum extract (QV0) suppresses pleural mesothelioma tumor growth in vitro and in vivo by mitochondrial dysfunction associated apoptosis. Front Oncol. 2023 Jul 5;13:1162027. doi: 10.3389/fonc.2023.1162027. eCollection 2023. PMID: 37476375.

Frentzas S, Kao S, Gao R, Zheng H, Rizwan A, Budha N, de la Hoz Pedroza L, Tan W, Meniawy T. AdvanTIG-105: a phase I dose escalation study of the anti-TIGIT monoclonal antibody ociperlimab in combination with tislelizumab in patients with advanced solid tumors. J Immunother Cancer. 2023 Oct;11(10):e005829. doi: 10.1136/jitc-2022-005829. PMID: 37857528.

Smith S, Kao S. PEMMELA: a promising regimen at the expense of toxicity. Lancet Oncol. 2023 Nov;24(11):1161-2. doi: 10.1016/S1470-2045(23)00512-0. Epub 2023 Oct 13. PMID: 37844596.

Soon JA, To YH, Alexander M, Trapani K, Ascierto PA, Athan S, Brown MP, Burge M, Haydon A, Hughes B, Itchins M, John T, Kao S, Koopman M, Li BT, Long GV, Loree JM, Markman B, Meniawy TM, Menzies AM, Nott L, Pavlakis N, Petrella TM, Popat S, Tie J, Xu W, Yip D, Zalcberg J, Solomon BJ, Gibbs P, McArthur GA, Franchini F, IJzerman M. A tailored approach to horizon scanning for cancer medicines. J Cancer Policy. 2023 Dec;38:100441. doi: 10.1016/j.jcpo.2023.100441. Epub 2023 Nov 20. PMID: 38008488.

Smith S, Boyer M, Kao S. Re-re-biopsy? How much tumor is enough in the era of precision oncology?. Asia Pac J Clin Oncol. 2023 Dec;19(6):581-4. doi: 10.1111/ajco.14030. Epub 2023 Oct 2. PMID: 37784252.

Yu HA, Goto Y, Hayashi H, Felip E, Chih-Hsin Yang J, Reck M, Yoh K, Lee SH, Paz-Ares L, Besse B, Bironzo P, Kim DW, Johnson ML, Wu YL, John T, Kao S, Kozuki T, Massarelli E, Patel J, Smit E, Reckamp KL, Dong Q, Shrestha P, Fan PD, Patel P, Sporchia A, Sternberg DW, Sellami D, Janne PA. HERTHENA-Lung01, a Phase II Trial of Patritumab Deruxtecan (HER3-DXd) in Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer After Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy and Platinum-Based Chemotherapy. J Clin Oncol. 2023 Dec 10;41(35):5363-75. doi: 10.1200/JCO.23.01476. Epub 2023 Sep 10. PMID: 37689979.

Tsai KH, Shi H, Parungao RJ, Naficy S, Ding X, Ding X, Hew JJ, Wang X, Chrzanowski W, Lavery GG, Li Z, Issler-Fisher AC, Chen J, Tan Q, Maitz PK, Cooper MS, Wang Y. Skin 11β-hydroxysteroid dehydrogenase type 1 enzyme expression regulates burn wound healing and can be targeted to modify scar characteristics. Burns Trauma. 2023 Jan 20;11:tkac052. doi: 10.1093/burnst/tkac052. eCollection 2023. PMID: 36694861.

Phan TH, Shi H, Denes CE, Cole AJ, Wang Y, Cheng YY, Hesselson D, Roelofs SH, Neely GG, Jang JH, Chrzanowski W. Advanced pathophysiology mimicking lung models for accelerated drug discovery. Biomater Res. 2023 Apr 26;27(1):35. doi: 10.1186/s40824-023-00366-x. PMID: 37098610.

Mani G, El-Kamand S, Wang B, Baker DL, Ataide SF, Artsimovitch I, Cubeddu L, Gamsjaeger R. A structural analysis of the nsp9 protein from the coronavirus MERS CoV reveals a conserved RNA binding interface. Proteins. 2024 Mar;92(3):418-26.  doi: 10.1002/prot.26630. Epub 2023 Nov 6. PMID: 37929701.

Choi WWY, Sanchez C, Li JJ, Dinarvand M, Adomat H, Ghaffari M, Khoja L, Vafaee F, Joshua AM, Chi KN, Guns EST, Hosseini-Beheshti E. Extracellular vesicles from biological fluids as potential markers in castration resistant prostate cancer. J Cancer Res Clin Oncol. 2023 Jul;149(8):4701-17.  doi: 10.1007/s00432-022-04391-6. Epub 2022 Oct 12.  PMID: 36222898.

Bazaz SR, Zhand S, Salomon R, Beheshti EH, Jin DY, Warkiani ME. ImmunoInertial microfluidics: A novel strategy for isolation of small EV subpopulations. Applied Materials Today. 2023 Feb;30:101730.  doi: 10.1016/j.apmt.2022.101730.

Ahmadzada T, Vijayan A, Vafaee F, Azimi A, Reid G, Clarke S, Kao S, Grau GE, Hosseini-Beheshti E. Small and Large Extracellular Vesicles Derived from Pleural Mesothelioma Cell Lines Offer Biomarker Potential. Cancers (Basel). 2023 Apr 18;15(8):2364.  doi: 10.3390/cancers15082364.  PMID: 37190292.

Kashani SA, Navabi R, Amini A, Hajinasrollah M, Jenab Y, Rabbani S, Nazari A, Pakzad M, Moazenchi M, Atrabi MJ, Samsonchi Z, Hezavehei M, Hosseini-Beheshti E, Shekari F, Hajizadeh-Saffar E, Baharvand H. Immunomodulatory potential of human clonal mesenchymal stem cells and their extracellular vesicle subpopulations in an inflammatory-mediated diabetic Rhesus monkey model. Life Sci. 2023 Sep 15;329:121950.  doi: 10.1016/j.lfs.2023.121950. Epub 2023 Jul 18.  PMID: 37473804.

Lee J, Currow D, Lovell M, Phillips JL, McLachlan A, Ritchie M, Brown L, Fazekas B, Aggarwal R, Seah D, Sheehan C, Chye R, Noble B, McCaffrey N, Aggarwal G, George R, Kow M, Ayoub C, Linton A, Sanderson C, Mittal D, Rao A, Prael G, Urban K, Vandersman P, Agar M. Lidocaine for Neuropathic Cancer Pain (LiCPain): study protocol for a mixed-methods pilot study. BMJ Open. 2023 Feb 21;13(2):e066125.  doi: 10.1136/bmjopen-2022-066125.  PMID: 36810169.

Chu GJ, Linton A, Kao S, Klebe S, Adelstein S, Yeo D, Rasko JEJ, Cooper WA. High mesothelin expression by immunohistochemistry predicts improved survival in pleural mesothelioma. Histopathology. 2023 Aug;83(2):202-10.  doi: 10.1111/his.14916. Epub 2023 Apr 11.  PMID: 37040900.

Davis A, Ke H, Kao S, Pavlakis N. An update on emerging therapeutic options for malignant pleural mesothelioma. Lung Cancer (Auckl). 2022 Mar 2;13:1-12. doi: 10.2147/LCTT.S288535. PMID: 35264891.

McLean AEB, Kao SC, Barnes DJ, Wong KKH, Scolyer RA, Cooper WA, Kohonen-Corish MRJ. The emerging role of the lung microbiome and its importance in non-small cell lung cancer diagnosis and treatment. Lung Cancer. 2022 Mar;165:124-32. doi: 10.1016/j.lungcan.2022.01.011. Epub 2022 Jan 20. PMID: 35123155.

McLean AEB, Kao SC, Barnes DJ, Wong KKH, Scolyer RA, Cooper WA, Kohonen-Corish MRJ. Corrigendum to “The emerging role of the lung microbiome and its importance in non-small cell lung cancer diagnosis and treatment” [Lung Cancer 165C (2022) 124-132]. Lung Cancer. 2022 Apr;166:252. doi: 10.1016/j.lungcan.2022.02.011. Epub 2022 Mar 9. PMID: 35279297.

Marabelle A, Cassier PA, Fakih M, Kao S, Nielsen D, Italiano A, Guren TK, van Dongen MGJ, Spencer K, Bariani GM, Ascierto PA, Santoro A, Shah M, Asselah J, Iqbal S, Takahashi S, Piha-Paul SA, Ott PA, Chatterjee A, Jin F, Norwood K, Delord JP. Pembrolizumab for previously treated advanced anal squamous cell carcinoma: results from the non-randomised, multicohort, multicentre, phase 2 KEYNOTE-158 study. Lancet Gastroenterol Hepatol. 2022 May;7(5):446-54. doi: 10.1016/S2468-1253(21)00382-4. Epub 2022 Feb 1. PMID: 35114169.

Lee JT, Mittal DL, Warby A, Kao S, Dhillon HM, Vardy JL. Dying of mesothelioma: A qualitative exploration of caregiver experiences. Eur J Cancer Care (Engl). 2022 Sep;31(5):e13627. doi: 10.1111/ecc.13627. Epub 2022 Jun 20. PMID: 35723508.

Hyland RA, Chrzanowska A, Hannaford-Turner K, Davis A, Ke H, Bradbury L, Nagrial A, McCaughan B, Hui R, van Zandwijk N, Takahashi K, Kao SC. Asbestos-related lung cancer: Clinical characteristics and survival outcomes in an Australian cohort seeking workers compensation. Asia Pac J Clin Oncol. 2022 Oct;18(5):e448-e55. doi: 10.1111/ajco.13664. Epub 2022 Jan 31. PMID: 35100476.

Kynaston A, Liu K, Davis A, Kao S, McKenzie C. A case of steroid responsive nivolumab induced cholangitis. Pathology. 2022 Oct;54(6):820-3. doi: 10.1016/j.pathol.2021.11.009. Epub 2022 Feb 10. PMID: 35153072.

Nindra U, Shahnam A, Stevens S, Pal A, Nagrial A, Lee J, Yip PY, Adam T, Boyer M, Kao S, Bray V. Elevated neutrophil-to-lymphocyte ratio (NLR) is associated with poorer progression-free survival in unresectable stage III NSCLC treated with consolidation durvalumab. Thorac Cancer. 2022 Nov;13(21):3058-62. doi: 10.1111/1759-7714.14646. Epub 2022 Sep 16. PMID: 36111516.

Itchins M, Ainsworth H, Alexander M, Dean S, Dharmaraj D, Pavlakis N, Clarke SJ, Brown C, Torres J, Saqib A, Ladwa R, O’Byrne K, Moore M, Yip PY, Solomon B, John T, Kao S, Mitchell P, Parakh S. A multi-center real-world experience of IMpower150 in oncogene driven tumors and CNS metastases. Clin Lung Cancer. 2022 Dec;23(8):702-8. doi: 10.1016/j.cllc.2022.07.016. Epub 2022 Aug 7. PMID: 36030187.

Heynemann S, Prosser N, Lee J, Mahar A, Anderson L, Kao S, Cooper WA. Squamous cell carcinoma differentiation at progression as a resistance mechanism in metastatic non-small cell lung carcinoma harbouring a targetable mutation. Pathology. 2022 Dec;54(7):935-8. doi: 10.1016/j.pathol.2022.02.004. Epub 2022 May 12. PMID: 35570027.

Johnson B, Zhuang L, Rath E, Yuen ML, Cheng NC, Shi H, Kao S, Reid G, Cheng YY. Exploring MicroRNA and exosome involvement in malignant pleural mesothelioma drug response. Cancers (Basel). 2022 Sep 30;14(19):4784. doi: 10.3390/cancers14194784. PMID: 36230710.

Shi H, Tsai KH, Ma D, Wang X, Desai R, Parungao RJ, Hunt NJ, Cheng YY, Zhang H, Xu Y, Simanainen U, Tan Q, Cooper MS, Handelsman DJ, Maitz PK, Wang Y. Controlled dual release of dihydrotestosterone and flutamide from polycaprolactone (PCL) electrospun scaffold accelerates burn wound healing. FASEB J. 2022 May;36(5):e22310. doi: 10.1096/fj.202101803R. PMID: 35394674.

Whittle K, Kao S, Clarke S, Grau GER, Hosseini-Beheshti E. Exploring the role of extracellular vesicles and their protein cargo in lung cancer metastasis: A review. Crit Rev Oncol Hematol. 2022 Mar;171:103603.  doi: 10.1016/j.critrevonc.2022.103603. Epub 2022 Jan 20.  PMID: 35066154.

Xu J, Yang KC, Go NE, Colborne S, Ho CJ, Hosseini-Beheshti E, Lystad AH, Simonsen A, Guns ET, Morin GB, Gorski SM. Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations. Autophagy. 2022 Nov;18(11):2547-60.  doi: 10.1080/15548627.2022.2039535. Epub 2022 Feb 28.  PMID: 35220892.

Al Halawani A, Mithieux SM, Yeo GC, Hosseini-Beheshti E, Weiss AS. Extracellular Vesicles: Interplay with the Extracellular Matrix and Modulated Cell Responses. Int J Mol Sci. 2022 Mar 21;23(6):3389.  doi: 10.3390/ijms23063389.  PMID: 35328809.

Hosseini-Giv N, Basas A, Hicks C, El-Omar E, El-Assaad F, Hosseini-Beheshti E. Bacterial extracellular vesicles and their novel therapeutic applications in health and cancer. Front Cell Infect Microbiol. 2022 Nov 11;12:962216.  doi: 10.3389/fcimb.2022.962216. eCollection 2022.  PMID: 36439225.

Batarseh AM, Vafaee F, Hosseini-Beheshti E, Safarchi A, Chen A, Cohen A, Juillard A, Hunt NH, Mariani M, Mitchell T, Grau GER. Investigation of Plasma-Derived Lipidome Profiles in Experimental Cerebral Malaria in a Mouse Model Study. Int J Mol Sci. 2022 Dec 28;24(1):501.  doi: 10.3390/ijms24010501.  PMID: 36613941.

Conduit C, Mak B, Qu W, Lulio JD, Burder R, Bressel M, Cusick T, Dhillon HM, Lourenco RA, Underhill C, Torres J, Crumbaker M, Honeyball F, Linton A, Allen R, Davis ID, Clark SJ, Horvath LG, Mahon KL. GUIDE: a randomised non-comparative phase II trial of biomarker-driven intermittent docetaxel versus standard-of-care docetaxel in metastatic castration-resistant prostate cancer (clinical trial protocol). Ther Adv Med Oncol. 2022 Apr 18;14:17588359221092486.  doi: 10.1177/17588359221092486. eCollection 2022.  PMID: 35465297.

Ke H, Kao S, Lee K, Takahashi K, Goh HP, Linton A. The minimum standard of care for managing malignant pleural mesothelioma in developing nations within the Asia-Pacific Region. Asia Pac J Clin Oncol. 2022 Jun;18(3):177-90.  doi: 10.1111/ajco.13611. Epub 2021 Jun 23.  PMID: 34161674.

Shi H, Rath EM, Lin RCY, Sarun KH, Clarke CJ, McCaughan BC, Ke H, Linton A, Lee K, Klebe S, Maitz J, Song K, Wang Y, Kao S, Cheng YY. 3-Dimensional mesothelioma spheroids provide closer to natural pathophysiological tumor microenvironment for drug response studies. Front Oncol. 2022 Aug 26;12:973576.  doi: 10.3389/fonc.2022.973576. eCollection 2022.  PMID: 36091141.

Ke H, Gill AJ, McKenzie C, Kench JG, Chan RCF, Pavlakis N, Fulham M, Koh C, Kao S. Malignant peritoneal mesothelioma with EWSR1-ATF1 fusion: a case report. JTO Clin Res Rep. 2021 Oct 11;2(11):100236. doi: 10.1016/j.jtocrr.2021.100236. eCollection 2021 Nov. PMID: 34766064, PMCID: PMC8569551.

Leal JL, Alexander M, Itchins M, Wright GM, Kao S, Hughes BGM, Pavlakis N, Clarke S, Gill AJ, Ainsworth H, Solomon B, John T. EGFR Exon 20 insertion mutations: clinicopathological characteristics and treatment outcomes in advanced non-small cell lung cancer. Clin Lung Cancer. 2021 Nov;22(6):e859-e69. doi: 10.1016/j.cllc.2021.04.009. Epub 2021 May 16. PMID: 34127383.

Johnson BW, Takahashi K, Cheng YY. Preclinical models and resources to facilitate basic science research on malignant mesothelioma–a review. Front Oncol. 2021 Nov 11;11:748444. doi: 10.3389/fonc.2021.748444. eCollection 2021. PMID: 34900693.

Yuen ML, Zhuang L, Rath EM, Yu T, Johnson B, Sarun KH, Wang Y, Kao S, Linton A, Clarke CJ, McCaughan BC, Takahashi K, Lee K, Cheng YY. The role of E-cadherin and microRNA on FAK inhibitor response in malignant pleural mesothelioma (MPM). Int J Mol Sci. 2021 Sep 23;22(19):10225. doi: 10.3390/ijms221910225. PMID: 34638565.

Shi H, Cheer K, Simanainen U, Lesmana B, Ma D, Hew JJ, Parungao RJ, Li Z, Cooper MS, Handelsman DJ, Maitz PK, Wang Y. The contradictory role of androgens in cutaneous and major burn wound healing. Burns Trauma. 2021 Apr 20;9:tkaa046. doi: 10.1093/burnst/tkaa046. eCollection 2021 Jan. PMID: 33928173.

Ryan ST, Hosseini-Beheshti E, Afrose D, Ding X, Xia B, Grau GE, Little CB, McClements L, Li JJ. Extracellular Vesicles from Mesenchymal Stromal Cells for the Treatment of Inflammation-Related Conditions. Int J Mol Sci. 2021 Mar 16;22(6):3023.  doi: 10.3390/ijms22063023.  PMID: 33809632.

Oey O, Ghaffari M, Li JJ, Hosseini-Beheshti E. Application of extracellular vesicles in the diagnosis and treatment of prostate cancer: Implications for clinical practice. Crit Rev Oncol Hematol. 2021 Nov;167:103495.  doi: 10.1016/j.critrevonc.2021.103495. Epub 2021 Oct 13.  PMID: 34655743.

Scheinberg T, Goodwin A, Ip E, Linton A, Mak B, Smith DP, Stockler MR, Strach MC, Tran B, Young AL, Zhang AY, Mahon KL, Horvath LG. Evaluation of a Mainstream Model of Genetic Testing for Men with Prostate Cancer. JCO Oncol Pract. 2021 Feb;17(2):e204-e216.  doi: 10.1200/OP.20.00399. Epub 2020 Sep 24.  PMID: 32970524.

Rozitis E, Johnson B, Cheng YY, Lee K. The Use of Immunohistochemistry, Fluorescence in situ Hybridization, and Emerging Epigenetic Markers in the Diagnosis of Malignant Pleural Mesothelioma (MPM): A Review. Front Oncol. 2020 Sep 9;10:1742. doi: doi.org/10.3389/fonc.2020.01742. eCollection 2020. PMID: 33014860.

Ahmadzada T, Kao S, Reid G, Clarke S, Grau GE, Hosseini-Beheshti E. Extracellular vesicles as biomarkers in malignant pleural mesothelioma: A review. Crit Rev Oncol Hematol. 2020 Jun;150:102949.  doi: 10.1016/j.critrevonc.2020.102949. Epub 2020 Apr 9.  PMID: 32330840.

Ahmadzada T, Cooper WA, Holmes M, Mahar A, Westman H, Gill AJ, Nordman I, Yip PY, Pal A, Zielinski R, Pavlakis N, Nagrial A, Daneshvar D, Brungs D, Karikios D, Aleksova V, Burn J, Asher R, Grau GE, Hosseini-Beheshti E, Reid G, Clarke S, Kao S. Retrospective Evaluation of the Use of Pembrolizumab in Malignant Mesothelioma in a Real-World Australian Population. JTO Clin Res Rep. 2020 Jul 16;1(4):100075.  doi: 10.1016/j.jtocrr.2020.100075. eCollection 2020 Nov.  PMID: 34589956.

Cheng YY, Rath EM, Linton A, Yuen ML, Takahashi K, Lee K. The Current Understanding Of Asbestos-Induced Epigenetic Changes Associated With Lung Cancer. Lung Cancer (Auckl). 2020 Jan 8;11:1-11.  doi: 10.2147/LCTT.S186843. eCollection 2020.  PMID: 32021524.

Cheng YY, Yuen ML, Rath EM, Johnson B, Zhuang L, Yu TK, Aleksova V, Linton A, Kao S, Clarke CJ, McCaughan BC, Takahashi K, Lee K. CDKN2A and MTAP Are Useful Biomarkers Detectable by Droplet Digital PCR in Malignant Pleural Mesothelioma: A Potential Alternative Method in Diagnosis Compared to Fluorescence In Situ Hybridisation. Front Oncol. 2020 Nov 13;10:579327.  doi: 10.3389/fonc.2020.579327. eCollection 2020.  PMID: 33304846.

Qian PC, Barry MA, Lu J, Pouliopoulos J, Mina A, Bandodkar S, Alvarez S, James V, Ronquillo J, Varikatt W, Thiagalingam A, Thomas SP. Transvascular Pacing of Aorticorenal Ganglia Provides a Testable Procedural Endpoint for Renal Artery Denervation. JACC Cardiovasc Interv. 2019 Jun 24;12(12):1109-20.  doi: 10.1016/j.jcin.2019.04.047.  PMID: 31221301.

Qian PC, Barry MA, Lu J, Al-Raisi S, Mina A, Ryan J, Bandodkar S, Alvarez S, James V, Ronquillo J, Varikatt W, Clayton Z, Chong J, Kovoor P, Pouliopoulos J, McEwan A, Thiagalingam A, Thomas SP. Transcatheter microwave ablation can deliver deep and circumferential perivascular nerve injury without significant arterial injury to provide effective renal denervation. J Hypertens. 2019 Oct;37(10):2083-92.  doi: 10.1097/HJH.0000000000002104.  PMID: 31033726.

Debs S, Cohen A, Hosseini-Beheshti E, Chimini G, Hunt NH, Grau GER. Interplay of extracellular vesicles and other players in cerebral malaria pathogenesis. Biochim Biophys Acta Gen Subj. 2019 Feb;1863(2):325-31.  doi: 10.1016/j.bbagen.2018.10.012. Epub 2018 Oct 17.  PMID: 30339917.

Hosseini-Beheshti E, Grau GER. Extracellular vesicles and microvascular pathology: Decoding the active dialogue. Microcirculation. 2019 Feb;26(2):e12485.  doi: 10.1111/micc.12485. Epub 2018 Jul 23.  PMID: 29923276.

Balaban S, Nassar ZD, Zhang AY, Hosseini-Beheshti E, Centenera MM, Schreuder M, Lin HM, Aishah A, Varney B, Liu-Fu F, Lee LS, Nagarajan SR, Shearer RF, Hardie RA, Raftopulos NL, Kakani MS, Saunders DN, Holst J, Horvath LG, Butler LM, Hoy AJ. Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer. Mol Cancer Res. 2019 Apr;17(4):949-62.  doi: 10.1158/1541-7786.MCR-18-0347. Epub 2019 Jan 15.  PMID: 30647103.

Li JJ, Hosseini-Beheshti E, Grau GE, Zreiqat H, Little CB. Stem Cell-Derived Extracellular Vesicles for Treating Joint Injury and Osteoarthritis. Nanomaterials (Basel). 2019 Feb 14;9(2):261.  doi: 10.3390/nano9020261.  PMID: 30769853.

Macia L, Nanan R, Hosseini-Beheshti E, Grau GE. Host- and microbiota-derived extracellular vesicles, immune function and disease development. Int J Mol Sci. 2019 Dec 22;21(1):107.  doi: 10.3390/ijms21010107.  PMID: 31877909.

Ahmadzada T, Lee K, Clarke C, Cooper WA, Linton A, McCaughan B, Asher R, Clarke S, Reid G, Kao S. High BIN1 expression has a favorable prognosis in malignant pleural mesothelioma and is associated with tumor infiltrating lymphocytes. Lung Cancer. 2019 Apr;130:35-41.  doi: 10.1016/j.lungcan.2019.02.005. Epub 2019 Feb 7.  PMID: 30885349.

Linton A, Blinman P, Kao S, van Zandwijk N. Patterns of care and survival of older patients with malignant pleural mesothelioma. J Geriatr Oncol. 2019 Jul;10(4):573-6.  doi: 10.1016/j.jgo.2019.02.013. Epub 2019 Mar 24.  PMID: 30917938.

Johnson BW, Burgess MW, Murray V, Aldrich-Wright JR, Temple MD. The interactions of novel mononuclear platinum-based complexes with DNA. BMC Cancer. 2018 Dec 22;18(1):1284. doi: 10.1186/s12885-018-5194-8. PMID: 30577821.

Hosseini-Beheshti E, Grau GER. Extracellular vesicles as mediators of immunopathology in infectious diseases. Immunol Cell Biol. 2018 Mar 25;96(7):694-703.  doi: 10.1111/imcb.12044. Online ahead of print.  PMID: 29577413.

Johnson TG, Schelch K, Cheng YY, Williams M, Sarun KH, Kirschner MB, Kao S, Linton A, Klebe S, McCaughan BC, Lin RCY, Pirker C, Berger W, Lasham A, van Zandwijk N, Reid G. Dysregulated Expression of the MicroRNA miR-137 and Its Target YBX1 Contribute to the Invasive Characteristics of Malignant Pleural Mesothelioma. J Thorac Oncol. 2018 Feb;13(2):258-72.  doi: 10.1016/j.jtho.2017.10.016. Epub 2017 Nov 4.  PMID: 29113949.

Cairns R, Alvarez-Guaita A, Martinez-Saludes I, Wason SJ, Hanh J, Nagarajan SR, Hosseini-Beheshti E, Monastyrskaya K, Hoy AJ, Buechler C, Enrich C, Rentero C, Grewal T. Role of hepatic Annexin A6 in fatty acid-induced lipid droplet formation. Exp Cell Res. 2017 Sep 15;358(2):397-410.  doi: 10.1016/j.yexcr.2017.07.015. Epub 2017 Jul 14.  PMID: 28712927.

Linton A, Soeberg M, Broome R, Kao S, van Zandwijk N. Geographic and socioeconomic factors in patients with malignant pleural mesothelioma in New South Wales and their impact upon clinical outcomes. Respirology. 2017 Jul;22(5):978-85.  doi: 10.1111/resp.12981. Epub 2017 Jan 31.  PMID: 28139858.

Kao SC, Cheng YY, Williams M, Kirschner MB, Madore J, Lum T, Sarun KH, Linton A, McCaughan B, Klebe S, van Zandwijk N, Scolyer RA, Boyer MJ, Cooper WA, Reid G. Tumor Suppressor microRNAs Contribute to the Regulation of PD-L1 Expression in Malignant Pleural Mesothelioma. J Thorac Oncol. 2017 Sep;12(9):1421-33.  doi: 10.1016/j.jtho.2017.05.024. Epub 2017 Jun 16.  PMID: 28629895.

van Zandwijk N, Pavlakis N, Kao SC, Linton A, Boyer MJ, Clarke S, Huynh Y, Chrzanowska A, Fulham MJ, Bailey DL, Cooper WA, Kritharides L, Ridley L, Pattison ST, MacDiarmid J, Brahmbhatt H, Reid G. Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study. Lancet Oncol. 2017 Oct;18(10):1386-96.  doi: 10.1016/S1470-2045(17)30621-6. Epub 2017 Sep 1.  PMID: 28870611.

Johnson BW, Murray V, Temple MD. Characterisation of the DNA sequence specificity, cellular toxicity and cross-linking properties of novel bispyridine-based dinuclear platinum complexes. BMC Cancer. 2016 May 25;16:333. doi: 10.1186/s12885-016-2368-0. PMID: 27225032.

Hosseini-Beheshti E, Choi W, Weiswald LB, Kharmate G, Ghaffari M, Roshan-Moniri M, Hassona MD, Chan L, Chin MY, Tai IT, Rennie PS, Fazli L, Tomlinson Guns ES. Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment. Oncotarget. 2016 Mar 22;7(12):14639-58.  doi: 10.18632/oncotarget.7052.  PMID: 26840259.

Kharmate G, Hosseini-Beheshti E, Caradec J, Chin MY, Tomlinson Guns ES. Epidermal Growth Factor Receptor in Prostate Cancer Derived Exosomes. PLoS One. 2016 May 6;11(5):e0154967.  doi: 10.1371/journal.pone.0154967. eCollection 2016.  PMID: 27152724.

Kim M, Truong NR, James V, Bosnjak L, Sandgren KJ, Harman AN, Nasr N, Bertram KM, Olbourne N, Sawleshwarkar S, McKinnon K, Cohen RC, Cunningham AL. Initial Interactions of Herpes Simplex Virus with Human Skin Dendritic Cells. Sexually Transmitted Infections. 2015;91(Suppl 2):A78-A9  LB1.5.  doi: 10.1136/sextrans-2015-052270.210.

Fokidis HB, Adomat HH, Kharmate G, Hosseini-Beheshti E, Guns ES, Soma KK. Regulation of local steroidogenesis in the brain and in prostate cancer: lessons learned from interdisciplinary collaboration. Front Neuroendocrinol. 2015 Jan;36:108-29.  doi: 10.1016/j.yfrne.2014.08.005. Epub 2014 Sep 16.  PMID: 25223867.

Minciacchi VR, You S, Spinelli C, Morley S, Zandian M, Aspuria PJ, Cavallini L, Ciardiello C, Reis-Sobreiro M, Morello M, Kharmate G, Jang SC, Kim DK, Hosseini-Beheshti E, Tomlinson Guns E, Gleave M, Gho YS, Mathivanan S, Yang W, Freeman MR, Di Vizio D. Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles. Oncotarget May 10. 2015;6(13):11327-41.  doi: 10.18632/oncotarget.3598.  PMID: 25857301.

Kirschner MB, Cheng YY, Armstrong NJ, Lin RC, Kao SC, Linton A, Klebe S, McCaughan BC, van Zandwijk N, Reid G. MiR-score: a novel 6-microRNA signature that predicts survival outcomes in patients with malignant pleural mesothelioma. Mol Oncol. 2015 Mar;9(3):715-26.  doi: 10.1016/j.molonc.2014.11.007. Epub 2014 Dec 2.  PMID: 25497279.

Williams M, Kirschner MB, Cheng YY, Hanh J, Weiss J, Mugridge N, Wright CM, Linton A, Kao SC, Edelman JJ, Vallely MP, McCaughan BC, Cooper W, Klebe S, Lin RC, Brahmbhatt H, MacDiarmid J, van Zandwijk N, Reid G. miR-193a-3p is a potential tumor suppressor in malignant pleural mesothelioma. Oncotarget. 2015 Sep 15;6(27):23480-95.  doi: 10.18632/oncotarget.4346.  PMID: 26125439.

Ming DS, Pham S, Deb S, Chin MY, Kharmate G, Adomat H, Hosseini-Beheshti E, Locke J, Guns ET. Pomegranate extracts impact the androgen biosynthesis pathways in prostate cancer models in vitro and in vivo. J Steroid Biochem Mol Biol. 2014 Sep;143:19-28.  doi: 10.1016/j.jsbmb.2014.02.006. Epub 2014 Feb 22.  PMID: 24565566.

Caradec J, Kharmate G, Hosseini-Beheshti E, Adomat H, Gleave M, Guns E. Reproducibility and efficiency of serum-derived exosome extraction methods. Clin Biochem. 2014 Sep;47(13-14):1286-92.  doi: 10.1016/j.clinbiochem.2014.06.011. Epub 2014 Jun 20.  PMID: 24956264.

Pham S, Deb S, Ming DS, Adomat H, Hosseini-Beheshti E, Zoubeidi A, Gleave M, Guns ES. Next-generation steroidogenesis inhibitors, dutasteride and abiraterone, attenuate but still do not eliminate androgen biosynthesis in 22RV1 cells in vitro. J Steroid Biochem Mol Biol. 2014 Oct;144 Pt B:436-44.  doi: 10.1016/j.jsbmb.2014.09.004. Epub 2014 Sep 6.  PMID: 25201454.

Linton A, Cheng YY, Griggs K, Schedlich L, Kirschner MB, Gattani S, Srikaran S, Kao SC-H, McCaughan BC, Klebe S, van Zandwijk N, Reid G. An RNAi-based screen reveals PLK1, CDK1 and NDC80 as potential therapeutic targets in malignant pleural mesothelioma. Br J Cancer. 2014 Jan 21;110(2):510-9.  doi: 10.1038/bjc.2013.731. Epub 2013 Dec 10.  PMID: 24327015.

Linton A, Pavlakis N, O’Connell R, Soeberg M, Kao S, Clarke S, Vardy J, van Zandwijk N. Factors associated with survival in a large series of patients with malignant pleural mesothelioma in New South Wales. Br J Cancer. 2014 Oct 28;111(9):1860-9.  doi: 10.1038/bjc.2014.478. Epub 2014 Sep 4.  PMID: 25188323.

Medbury HJ, James V, Ngo J, Hitos K, Wang Y, Harris DC, Fletcher JP. Differing association of macrophage subsets with atherosclerotic plaque stability. Int Angiol. 2013 Feb;32(1):74-84.  PMID: 23435395.

Linton A, Kao S, Vardy J, Clarke S, van Zandwijk N, Klebe S. Immunohistochemistry in the diagnosis of malignant pleural mesothelioma: trends in Australia and a literature review. Asia Pac J Clin Oncol. 2013 Sep;9(3):273-9.  doi: 10.1111/ajco.12043. Epub 2012 Nov 21.  PMID: 23167246.

Linton A, Pond G, Clarke S, Vardy J, Galsky M, Sonpavde G. Glasgow prognostic score as a prognostic factor in metastatic castration-resistant prostate cancer treated with docetaxel-based chemotherapy. Clin Genitourin Cancer. 2013 Dec;11(4):423-30.  doi: 10.1016/j.clgc.2013.04.020. Epub 2013 Jun 28.  PMID: 23816526.

Hosseini-Beheshti E, Lund ST, Kitts DD. Characterization of Antioxidant Capacity from Fruits with Distinct Anthocyanin Biosynthetic Pathways. J Nutr Food Sci. 2012;2(1):1000122.  doi: 10.4172/2155-9600.1000122.

Hosseini-Beheshti E, Pham S, Adomat H, Li N, Tomlinson Guns ES. Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Mol Cell Proteomics. 2012 Oct;11(10):863-85.  doi: 10.1074/mcp.M111.014845. Epub 2012 Jun 21.  PMID: 22723089.

Linton A, Vardy J, Clarke S, van Zandwijk N. The ticking time-bomb of asbestos: its insidious role in the development of malignant mesothelioma. Crit Rev Oncol Hematol. 2012 Nov;84(2):200-12.  doi: 10.1016/j.critrevonc.2012.03.001. Epub 2012 Mar 27.  PMID: 22459593.

Linton A, van Zandwijk N, Reid G, Clarke S, Cao C, Kao S. Inflammation in malignant mesothelioma – friend or foe? Ann Cardiothorac Surg. 2012 Nov;1(4):516-22.  doi: 10.3978/j.issn.2225-319X.2012.10.02.  PMID: 23977546.

van Zandwijk N, Reid G, Linton A, Kao S. Radical surgery for malignant pleural mesothelioma: have we identified the appropriate selection tools? Ann Cardiothorac Surg. 2012 Nov;1(4):481-6.  doi: 10.3978/j.issn.2225-319X.2012.10.01.  PMID: 23977540.

Hosseini-Beheshti E, Lund ST, Kitts DD. Comparison of Antioxidant Activity of Two Soft Fruits Sources with Different Anthocyanin Composition. Acta Horticulturae. 2009. 841:519-522.  doi: 10.17660/ActaHortic.2009.841.73.

Linton A, Grimison P. Testicular Cancer. Australian Doctor: How to Treat. 2009 Jun 17: 33-40.

Kewalramani G, Puthanveetil P, Kim MS, Wang F, Lee V, Hau N, Beheshti E, Ng N, Abrahani A, Rodrigues B. Acute dexamethasone-induced increase in cardiac lipoprotein lipase requires activation of both Akt and stress kinases. Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E137-47. doi: 10.1152/ajpendo.00004.2008. Epub 2008 May 6.  PMID: 18460599.

Kim MS, Wang F, Puthanveetil P, Kewalramani G, Hosseini-Beheshti E, Ng N, Wang Y, Kumar U, Innis S, Proud CG, Abrahani A, Rodrigues B. Protein kinase D is a Key Regulator of Cardiomyocyte Lipoprotein Lipase Secretion after Diabetes. Circ Res. 2008 Aug 1;103(3):252-60. doi: 10.1161/CIRCRESAHA.108.178681. Epub 2008 Jun 26. PMID: 18583709.

Puthanveetil P, Wang F, Kewalramani G, Kim MS, Hosseini-Beheshti E, Ng N, Lau W, Pulinilkunnil T, Allard M, Abrahani A, Rodrigues B. Cardiac glycogen accumulation after dexamethasone is regulated by AMPK. Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1753-62.  doi: 10.1152/ajpheart.518.2008.  Epub 2008 Aug 29.  PMID: 18757479.